The hunt is on as a government assassin comes out of retirement to track down a killer extraterrestrial murdering the former members of his team in this science fiction thriller set in an alternate future America.

Following the incident in the Southeast Asia Union in 2116, Shinya Kogami resumes his vagrant journey. In a small South Asian nation, Kogami rescues a bus of refugees under attack by armed guerrilla forces. Among the refugees is a young lady by the name of Tenzin, who begs Kogami to teach her how to retaliate against the enemy.

A runaway vehicle crashes into the Public Safety Bureau Building. The driver is identified as Izumi Yasaka, a psychological counselor at the Sanctuary, a Latent Criminal Isolation Facility in Aomori Prefecture. But right before her interrogation, Inspector Mika Shimotsuki and Enforcer Nobuchika Ginoza are tasked with promptly escorting Yasaka back to Aomori. What awaits them there is a False Paradise.

Os primeiros dias de Deunan e seu parceiro ciborgue num mundo desolador devastado pela terceira Guerra Mundial onde procuram a cidade de Olympus. História de Masamune Shirow, também responsável pelas sagas Ghost in the Shell e Blood: The Last Vampire.